Instance ID10850
Regular Expression(Y)xNx
Motif InstanceYVNV
Bait Uniprot AccessionP08581
Bait Uniprot IdentifierMET_HUMAN
Bait Gene NameMET
Bait OrganismHomo sapiens (Human)
Sequence Position1356-1359
Critical ResiduesP1
Motif PTM(s)Phosphorylation at Tyr-P1
Secondary StructureBeta turn
Experimental Method(s)X-ray crystallography
Interaction ID20850
Interacting DomainSH2 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11063574, 12475979
CommentsPhosphorylation of Tyr-1356 in Human Proto-oncogene c-Met creates a docking site for the SH2-domain of the human Adapter protein GRB2

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)