Instance ID10852
Regular Expression(Y)xNx
Motif InstanceYVNV
Bait Uniprot AccessionO54957
Bait Uniprot IdentifierLAT_MOUSE
Bait Gene NameLat
Bait OrganismMus musculus (Mouse)
Sequence Position175-178
Critical ResiduesP1
Motif PTM(s)Phosphorylation at Tyr-P1
Secondary StructureUnknown
Experimental Method(s)Co-IP; Mutation analysis
Interaction ID20852
Interacting DomainSH2 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10811803
CommentsTyrosine-phosphorylated (Y175) mouse 36 kDa phospho-tyrosine adapter protein Lat binds to the SH2 domain of mouse Grb2 adaptor protein

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)