Instance ID10859
Regular Expression(Y)[QDEVAIL][DENPYHI][IPVGAHS]
Motif InstanceYEEI
Bait Uniprot AccessionP03079
Bait Uniprot IdentifierMT_POVHA
Bait Gene NameNot Available
Bait OrganismHamster polyomavirus (HaPyV)
Sequence Position324-327
Critical ResiduesP1
Motif PTM(s)Phosphorylation at Tyr-P1
Secondary StructureUnknown
Experimental Method(s)Co-IP; Mutation analysis
Interaction ID20859
Interacting DomainSH2 domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)8985339
CommentsMiddle-T antigen of hamster polyomavirus (HamT) associates with the SH2 domain of Proto-oncogene c-Fyn through phosphorylated Tyr-324, which is essential for the oncogenicity of HamT

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)