Instance ID10861
Regular Expression(Y)[QDEVAIL][DENPYHI][IPVGAHS]
Motif InstanceYDEV
Bait Uniprot AccessionO60500
Bait Uniprot IdentifierNPHN_HUMAN
Bait Gene NameNPHS1
Bait OrganismHomo sapiens (Human)
Sequence Position1176-1179
Critical ResiduesP1
Motif PTM(s)Phosphorylation at Tyr-P1
Secondary StructureUnknown
Experimental Method(s)Co-IP; Mutation analysis
Interaction ID20861
Interacting DomainSH2 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)16525419
CommentsThe cytoplasmic tail of human Renal glomerulus-specific cell adhesion receptor Nephrin selectively binds the mouse Nck adaptor protein, which in turn control the podocyte cytoskeleton

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)