Instance ID10864
Regular Expression(Y)[QDEVAIL][DENPYHI][IPVGAHS]
Motif InstanceYVPP
Bait Uniprot AccessionQ14118
Bait Uniprot IdentifierDAG1_HUMAN
Bait Gene NameDAG1
Bait OrganismHomo sapiens (Human)
Sequence Position892-895
Critical ResiduesP1
Motif PTM(s)Phosphorylation at Tyr-P1
Secondary StructureUnknown
Experimental Method(s)Co-IP; Pull down; Peptide binding to perpetrator; Mutation analysis
Interaction ID20864
Interacting DomainSH2 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11724572
CommentsTyrosine phosphorylation of beta-dystroglycan at Tyr-892 allows its interaction with the SH2 domain of Proto-oncogene c-Fyn

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)