Instance ID10874
Regular ExpressionG(Y)[KQ]xF
Motif InstanceGYKAF
Bait Uniprot AccessionP24394
Bait Uniprot IdentifierIL4RA_HUMAN
Bait Gene NameIL4R
Bait OrganismHomo sapiens (Human)
Sequence Position602-606
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; EMSA
Interaction ID20874
Interacting DomainSH2 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9712048
CommentsHuman Interleukin-4 receptor subunit alpha (IL4R) gene regulation domain contains a tyrosine-based sequence that are essential for the proper activation of Human STAT6 and can function as a mobile STAT6 activation cassette

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)