Instance ID10893
Regular ExpressionPxxPx[KR]
Motif InstancePLSPSR
Bait Uniprot AccessionP01106
Bait Uniprot IdentifierMYC_HUMAN
Bait Gene NameMYC
Bait OrganismHomo sapiens (Human)
Sequence Position60-65
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructurePPII helix
Experimental Method(s)NMR; Y2H
Interaction ID20893
Interacting DomainSH3 domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)15992821
CommentsThe consensus class II SH3-binding motif in the N terminus of the Human c-Myc oncoprotein interacts with the C-terminal SH3 domain of human BIN1, a ubiquitously expressed nucleocytoplasmic protein with features of a tumor suppressor

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)