Instance ID10895
Regular ExpressionPxxPx[KR]
Motif InstancePAPPMR
Bait Uniprot AccessionQ13153
Bait Uniprot IdentifierPAK1_HUMAN
Bait Gene NamePAK1
Bait OrganismHomo sapiens (Human)
Sequence Position13-18
Critical ResiduesP1
Motif PTM(s)Unknown
Secondary StructurePPII helix
Experimental Method(s)Y2H; Pull down; Mutation analysis
Interaction ID20895
Interacting DomainSH3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)8798379
CommentsThe association between human NCK adaptor protein 1 (NCK1) and human Serine/threonine-protein kinase PAK1 is mediated by the second SH3 domain of NCK1 and a proline-rich sequence in the amino terminus of PAK1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)