Instance ID10896
Regular ExpressionPxxPx[KR]
Motif InstancePAPPSR
Bait Uniprot AccessionQ13444
Bait Uniprot IdentifierADA15_HUMAN
Bait Gene NameADAM15
Bait OrganismHomo sapiens (Human)
Sequence Position767-772
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructurePPII helix
Experimental Method(s)Peptide array; Solid phase assay; Mutation analysis
Interaction ID20896
Interacting DomainSH3 domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)19718658
CommentsThe consensus class II SH3-binding motif in Human Disintegrin and metalloproteinase domain-containing protein 15 (ADAM15), that interacts with the SH3 domain of Human Proto-oncogene tyrosine-protein kinase Src (SRC)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)