Instance ID10897
Regular Expressionxxx[PV]xxP
Motif InstanceYGPVLSP
Bait Uniprot AccessionO15350
Bait Uniprot IdentifierP73_HUMAN
Bait Gene NameTP73
Bait OrganismHomo sapiens (Human)
Sequence Position407-413
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Co-IP
Interaction ID20897
Interacting DomainSH3 domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)10391251
CommentsHuman Proto-oncogene c-Abl (ABL1) binds to human Tumor protein p73 (TP73) via its SH3 domain and thereby stimulates p73-mediated transactivation and apoptosis in response to DNA damage


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)