Instance ID10901
Regular Expressionxxx[PV]xxP
Motif InstanceVPPPVPP
Bait Uniprot AccessionQ62245
Bait Uniprot IdentifierSOS1_MOUSE
Bait Gene NameSos1
Bait OrganismMus musculus (Mouse)
Sequence Position1135-1141
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructurePPII helix
Experimental Method(s)NMR
Interaction ID20901
Interacting DomainSH3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9135122
CommentsInteraction between the N-terminal SH3 domain of Mouse growth factor receptor-bound protein 2 (Grb2) with the mouse Son-of-Sevenless (Sos) protein is mediated by a proline-rich peptide of the mouse Sos1 sequence

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)