Instance ID10903
Regular Expressionxxx[PV]xxP
Motif InstancePHVVDLP
Bait Uniprot AccessionP69616
Bait Uniprot IdentifierORF3_HEVBU
Bait Gene NameORF_Name:ORF3
Bait OrganismHepatitis E virus genotype 1 (isolate Human/Burma) (HEV-1)
Sequence Position102-108
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructurePPII helix
Experimental Method(s)Mutation analysis; Y2H; Pull down
Interaction ID20903
Interacting DomainSH3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11518702
CommentsThe ORF3 protein of Hepatitis E virus binds to the SH3 domain of human Proto-oncogene tyrosine-protein kinase SRC through one of its PXXP motifs (102-108)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)