Instance ID10906
Regular Expressionxxx[PV]xxP
Motif InstanceSHRPPPP
Bait Uniprot AccessionP06729
Bait Uniprot IdentifierCD2_HUMAN
Bait Gene NameCD2
Bait OrganismHomo sapiens (Human)
Sequence Position294-300
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructurePPII helix
Experimental Method(s)NMR; Competition binding
Interaction ID20906
Interacting DomainSH3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12426371
CommentsInteraction of membrane-proximal proline-rich motif in the human T-cell surface antigen CD2 cytoplasmic tail with the SH3 domain of human Tyrosine-protein kinase FYN

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)