Instance ID10907
Regular Expressionxxx[PV]xxP
Motif InstanceSPPPYVP
Bait Uniprot AccessionQ14118
Bait Uniprot IdentifierDAG1_HUMAN
Bait Gene NameDAG1
Bait OrganismHomo sapiens (Human)
Sequence Position888-894
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructurePPII helix
Experimental Method(s)Solid phase assay; SPR
Interaction ID20907
Interacting DomainSH3 domain
Disease Association(s)Unknown
Inhibitor(s)Dystrophin
Reference(s)10903901
CommentsHigh-affinity interaction between the SH3 domains of human Adapter protein GRB2 and a proline-rich region within human Beta-dystroglycan which is inhibited by dystrophin

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)