Instance ID10912
Regular ExpressionPxxDY
Motif InstancePPVDY
Bait Uniprot AccessionQ8IZP0
Bait Uniprot IdentifierABI1_HUMAN
Bait Gene NameABI1
Bait OrganismHomo sapiens (Human)
Sequence Position417-421
Critical ResiduesP1; P4; P5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Alanine scanning; Far-western blotting; ELISA; Pull down(GST tag)
Interaction ID20912
Interacting DomainSH3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10508163
CommentsThe SH3 domain of human Epidermal growth factor receptor kinase substrate 8 (EPS8) binds to the PXXDY consensus motif found in human Abl interactor 1 (ABI1) or e3B1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)