Instance ID10914
Regular ExpressionPxxDY
Motif InstancePNPDY
Bait Uniprot AccessionP07766
Bait Uniprot IdentifierCD3E_HUMAN
Bait Gene NameCD3E
Bait OrganismHomo sapiens (Human)
Sequence Position184-188
Critical ResiduesP5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Pull down; Display technology; Co-IP; Mutation analysis
Interaction ID20914
Interacting DomainSH3 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)17617578
CommentsThe PxxDY motif of human T-cell surface glycoprotein CD3 epsilon (CD3E) mediates binding to the N-terminal SH3 domain of human Cytoplasmic protein NCK1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)