Instance ID10917
Regular ExpressionxPxAxVxP[^P]
Motif InstanceAPTAVVLPH
Bait Uniprot AccessionQ16633
Bait Uniprot IdentifierOBF1_HUMAN
Bait Gene NamePOU2AF1
Bait OrganismHomo sapiens (Human)
Sequence Position46-54
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Pull down(GST tag); Mammalian two-hybrid assay; Classical fluorescence spectroscopy
Interaction ID20917
Interacting DomainTRAF-like domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11483518
CommentsThe PxAxVxP motif in human B-cell-specific coactivator OBF-1/BOB-1 (POU2AF1) that confer a high-affinity binding to human E3 ubiquitin-protein ligase SIAH2

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)