Instance ID10920
Regular ExpressionxPxAxVxP[^P]
Motif InstanceKPAAVVAPI
Bait Uniprot AccessionQ9HB71
Bait Uniprot IdentifierCYBP_HUMAN
Bait Gene NameCACYBP
Bait OrganismHomo sapiens (Human)
Sequence Position59-67
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)X-ray crystallography; Y2H; Co-IP
Interaction ID20920
Interacting DomainTRAF-like domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)16085652, 11389839
CommentsThe PxAxVxP motif in human Calcyclin-binding protein (CACYBP)/Siah-interacting protein that mediates binding to and degradation by human E3 ubiquitin-protein ligase SIAH1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)