Instance ID10924
Regular ExpressionxPxAxVxP[^P]
Motif InstanceRPTAAVTPI
Bait Uniprot AccessionQ7Z6J0
Bait Uniprot IdentifierSH3R1_HUMAN
Bait Gene NameSH3RF1
Bait OrganismHomo sapiens (Human)
Sequence Position600-608
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Y2H; Co-IP
Interaction ID20924
Interacting DomainTRAF-like domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)16230351
CommentsHuman E3 ubiquitin-protein ligase SIAH1 is a binding partner for E3 ubiquitin-protein ligase SH3RF1/ POSH (Plenty of SH3s), a scaffold component of the apoptotic JNK pathway, and thus contributes to promotion of apoptotic death by activating the JNK pathway

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)