Instance ID10925
Regular Expression[LIV]xx[LM]LxAAx[FY][LI]
Motif InstanceIQMLLEAADYL
Bait Uniprot AccessionQ05195
Bait Uniprot IdentifierMAD1_HUMAN
Bait Gene NameMXD1
Bait OrganismHomo sapiens (Human)
Sequence Position9-19
Critical ResiduesP2; P6; P9
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)NMR; Mutation analysis
Interaction ID20925
Interacting DomainPAH2 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15235594, 11101889
CommentsThe N-terminal region of human Max dimerization protein 1 (MXD1) binds the second paired amphipathic helix (PAH) domain (PAH2) of mouse Transcriptional corepressor Sin3a through a novel helical fold

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)