Instance ID10927
Regular Expression[FHYM]xA[AV]x[VAC]L[MV]x[MI]
Motif InstanceMEAVEALVCM
Bait Uniprot AccessionO14901
Bait Uniprot IdentifierKLF11_HUMAN
Bait Gene NameKLF11
Bait OrganismHomo sapiens (Human)
Sequence Position45-54
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Pull down(GST tag)
Interaction ID20927
Interacting DomainPAH2 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11438660
CommentsA conserved alpha-helical motif located within the repression domain (R1) of human Krueppel-like factor 11 (KLF11/TIEG2) specifically associates with the second paired amphipathic helix (PAH2) domain of mouse Transcriptional corepressor Sin3a

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)