Instance ID10930
Regular Expression[FA]x[LA][LV][LVI]xx[AM]
Motif InstanceFQLLVDVA
Bait Uniprot AccessionQ15583
Bait Uniprot IdentifierTGIF1_HUMAN
Bait Gene NameTGIF1
Bait OrganismHomo sapiens (Human)
Sequence Position379-386
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Y2H
Interaction ID20930
Interacting DomainPAH2 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11571228
CommentsThe Human homeodomain protein TG-interacting factor (TGIF) interacts directly with the PAH2 domain of mouse Transcriptional corepressor Sin3a and thereby recruits mSin3 to a TGFbeta-activated Smad complex

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)