Instance ID10931
Regular ExpressionRF[^P][IV]x
Motif InstanceRFQVT
Bait Uniprot AccessionQ80UE6
Bait Uniprot IdentifierWNK4_MOUSE
Bait Gene NameWnk4
Bait OrganismMus musculus (Mouse)
Sequence Position996-1000
Critical ResiduesP2
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Y2H; Mutation analysis
Interaction ID20931
Interacting DomainConserved C-Terminal (CCT) domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15930150
CommentsVolume sensitivity of cation-chloride cotransporters is modulated by functional interaction between the conserved C-terminal (CCT) domain of mouse Ste20-related kinase Stk39/Spak and the RFxV docking motif of mouse Serine/threonine-protein kinase Wnk4

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)