Instance ID10943
Regular ExpressionRF[^P][IV]x
Motif InstanceRFQVT
Bait Uniprot AccessionQ96J92
Bait Uniprot IdentifierWNK4_HUMAN
Bait Gene NameWNK4
Bait OrganismHomo sapiens (Human)
Sequence Position1016-1020
Critical ResiduesP1; P2; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)SPR; X-ray crystallography; Mutation analysis
Interaction ID20943
Interacting DomainConserved C-Terminal (CCT) domain
Disease Association(s)Pseudohypoaldosteronism type 2 (PHA2)
Inhibitor(s)Unknown
Reference(s)17721439
CommentsHuman Serine/threonine-protein kinase WNK4 interacts with the conserved C-terminal (CCT) domain of human Oxidative stress-responsive 1 protein (OXSR1) through its RFxV docking motif

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)