Instance ID10957
Regular Expression[ILV](x[ILV]|[ILV]|[ILV]x)[ILV][STDE]{1,10}
Motif InstanceILLDSD
Bait Uniprot AccessionO00257
Bait Uniprot IdentifierCBX4_HUMAN
Bait Gene NameCBX4
Bait OrganismHomo sapiens (Human)
Sequence Position463-468
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureExtended conformation
Experimental Method(s)Mutation analysis; Y2H; Pull down(GST tag); Competition binding
Interaction ID20957
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)20176810
CommentsThe SUMO E3 ligase activity of human E3 SUMO-protein ligase CBX4 is coordinated through a SUMO interaction motif (SIM) that mediates interactions with human Small ubiquitin-related modifier 1 (SUMO1)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)