Instance ID10970
Regular Expression[ILV](x[ILV]|[ILV]|[ILV]x)[ILV][STDE]{1,10}
Motif InstanceVIDLT
Bait Uniprot AccessionO75928
Bait Uniprot IdentifierPIAS2_HUMAN
Bait Gene NamePIAS2
Bait OrganismHomo sapiens (Human)
Sequence Position469-473
Critical ResiduesP1; P2; P4; P5
Motif PTM(s)Unknown
Secondary StructureExtended conformation
Experimental Method(s)ITC; NMR; Alanine scanning; Mutation analysis
Interaction ID20970
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)16204249, 15388847, 16524884
CommentsThe SUMO-interacting motif (SIM) of human E3 SUMO-protein ligase PIAS2 that mediates interactions with human Small ubiquitin-related modifier 1 (SUMO1)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)