Instance ID10977
Regular Expression[ILV](x[ILV]|[ILV]|[ILV]x)[ILV][STDE]{1,10}
Motif InstanceIIISDSDDDDDE
Bait Uniprot AccessionQ7Z333
Bait Uniprot IdentifierSETX_HUMAN
Bait Gene NameSETX
Bait OrganismHomo sapiens (Human)
Sequence Position1014-1025
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureExtended conformation
Experimental Method(s)Y2H; Mutation analysis
Interaction ID20977
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)16524884
CommentsThe SUMO-interacting motif (SIM) of human Senataxin (SETX), a newly identified helicase mutated in patients suffering from ataxia-ocular apraxia 2, that mediates interactions with human Small ubiquitin-related modifier 1 (SUMO1)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)