Instance ID10986
Regular Expression[STDE]{1,10}[ILV](x[ILV]|[ILV]|[ILV]x)[ILV]
Motif InstanceDDDVLIV
Bait Uniprot AccessionP49792
Bait Uniprot IdentifierRBP2_HUMAN
Bait Gene NameRANBP2
Bait OrganismHomo sapiens (Human)
Sequence Position2629-2635
Critical ResiduesP4; P6; P7
Motif PTM(s)Unknown
Secondary StructureExtended conformation
Experimental Method(s)Y2H; X-ray crystallography; Pull down; Mutation analysis
Interaction ID20986
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)16524884, 15931224, 15388847
CommentsInverted version of the SUMO-interacting motif (SIM) of human E3 SUMO-protein ligase RANBP2 that mediates specific interaction with sumoylated human Ran GTPase-activating protein 1 (RANGAP1)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)