Instance ID10993
Regular Expression([KR][^ED]{0,5}[ST]xIP[^ED]{5,5})|([^ED]{5,5}[ST]xIP[^ED]{0,5}[KR])
Motif InstanceSTAKPSKIPTPQRK
Bait Uniprot AccessionQ03001
Bait Uniprot IdentifierDYST_HUMAN
Bait Gene NameDST
Bait OrganismHomo sapiens (Human)
Sequence Position7545-7558
Critical ResiduesP5; P6
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)X-ray crystallography; Classical fluorescence spectroscopy; Pull down; ITC; Mutation analysis
Interaction ID20993
Interacting DomainEBH domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)19632184
CommentsThe C-terminal EBH domain of human End-binding protein 1 (EB1) or MAPRE1 binds to the SxIP motif of human Dystonin (DST)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)