Instance ID11003
Regular ExpressionxRxx[PGAV][DEIP]Gx
Motif InstanceYRQSPDGA
Bait Uniprot AccessionQ9UIQ6
Bait Uniprot IdentifierLCAP_HUMAN
Bait Gene NameLNPEP
Bait OrganismHomo sapiens (Human)
Sequence Position95-102
Critical ResiduesP2; P5; P6; P7
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Pull down(GST tag); Alanine scanning; X-ray crystallography
Interaction ID21003
Interacting DomainAnkyrin repeat domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12080061, 22153077
CommentsThe N-terminal region of ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif in human Leucyl-cystinyl aminopeptidase (LNPEP)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)