Instance ID11009
Regular ExpressionxRxx[PGAV][DEIP]Gx
Motif InstanceERGEAEGC
Bait Uniprot AccessionQ9NRI5
Bait Uniprot IdentifierDISC1_HUMAN
Bait Gene NameDISC1
Bait OrganismHomo sapiens (Human)
Sequence Position222-229
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Fluorescence polarization spectroscopy; Mutation analysis; Co-IP
Interaction ID21009
Interacting DomainAnkyrin repeat domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)22153077
CommentsThe N-terminal region of ankyrin repeats in human poly(ADP-ribose)polymerase Tankyrase-2 (TNKS2) interacts with the Tankyrase-binding motif in human Disrupted in schizophrenia 1 protein (DISC1)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)