Instance ID11016
Regular Expression[PSAT]x[QE]E
Motif InstancePEQE
Bait Uniprot AccessionP28908
Bait Uniprot IdentifierTNR8_HUMAN
Bait Gene NameTNFRSF8
Bait OrganismHomo sapiens (Human)
Sequence Position561-564
Critical ResiduesP1; P3; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; Y2H; Co-IP; Pull down(GST tag)
Interaction ID21016
Interacting DomainMATH domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)8662842
CommentsHuman Lymphocyte activation antigen CD30, a member of the tumor necrosis factor (TNF) receptor family of proteins, initiate intracellular signaling by recruiting the C-domain of human TNF receptor-associated factor 3 (TRAF3)/CRAF1 through a consensus motif in its cytoplasmic tail

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)