Instance ID11017
Regular Expression[PSAT]x[QE]E
Motif InstancePVQE
Bait Uniprot AccessionP25942
Bait Uniprot IdentifierTNR5_HUMAN
Bait Gene NameCD40
Bait OrganismHomo sapiens (Human)
Sequence Position250-253
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructurePPII helix
Experimental Method(s)X-ray crystallography; Peptide Binding Assay
Interaction ID21017
Interacting DomainMATH domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10518213, 9718306
CommentsHuman B-cell surface antigen CD40, a TNF receptor superfamily member, associates with the human TNF receptor-associated factor 2 (TRAF2) through a TRAF2 binding site in the CD40 cytoplasmic domain

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)