Instance ID11031
Regular ExpressionxxPxExx[FYWHDE]x
Motif InstanceNTPVEDDEM
Bait Uniprot AccessionP10221
Bait Uniprot IdentifierUL37_HHV11
Bait Gene NameUL37
Bait OrganismHuman herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Sequence Position1097-1105
Critical ResiduesP5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Pull down; Co-IP; Mutation analysis
Interaction ID21031
Interacting DomainMATH domain
Disease Association(s)Herpes simplex virus (HSV) infection
Inhibitor(s)Unknown
Reference(s)18682563
CommentsHerpesvirus Capsid assembly protein UL37 contains a TRAF6 binding site that is required for interaction with human TNF receptor-associated factor 6 (TRAF6) and activation of NF-kappaB

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)