Instance ID11032
Regular Expression[FY]xLxP
Motif InstanceFTLKP
Bait Uniprot AccessionQ96BK5
Bait Uniprot IdentifierPINX1_HUMAN
Bait Gene NamePINX1
Bait OrganismHomo sapiens (Human)
Sequence Position289-293
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)ITC
Interaction ID21032
Interacting DomainTRFH domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)18202258
CommentsThe telomeric repeat binding factor (TRF) homology (TRFH) domain of human Telomeric repeat-binding factor 1 (TERF1/PIN2/TRF1) recognizes and directly interacts with the [Y/F]XL motif in human PIN2/TERF1-interacting telomerase inhibitor 1 (PINX1) and regulates telomere maintenance

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)