Instance ID11035
Regular Expression[KR]{1,4}[KR]x[KR]Wx
Motif InstanceRKRRWS
Bait Uniprot AccessionP54253
Bait Uniprot IdentifierATX1_HUMAN
Bait Gene NameATXN1
Bait OrganismHomo sapiens (Human)
Sequence Position770-775
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)NMR; ITC; Competition binding
Interaction ID21035
Interacting DomainUHM domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)20037628
CommentsHuman Ataxin-1 (ATXN1), a member of the polyglutamine (polyQ) expanded protein family, interacts with and influences the function of the splicing factor U2AF65 (U2AF2) via its UHM ligand motif (ULM)

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)