Instance ID11040
Regular Expression[PA][^P][^FYWIL]S[^P]
Motif InstancePGGSR
Bait Uniprot AccessionP04637
Bait Uniprot IdentifierP53_HUMAN
Bait Gene NameTP53
Bait OrganismHomo sapiens (Human)
Sequence Position359-363
Critical ResiduesP1; P4
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)X-ray crystallography; Mutation analysis; Classical fluorescence spectroscopy; ITC
Interaction ID21040
Interacting DomainMATH domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)16474402, 16402859
CommentsThe N-terminal TRAF-like domain of human Deubiquitinating enzyme USP7 binds to a P/AXXS motif (359-363) in human Cellular tumor antigen P53

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)