Instance ID11043
Regular Expression[PA][^P][^FYWIL]S[^P]
Motif InstanceAHSSE
Bait Uniprot AccessionO15151
Bait Uniprot IdentifierMDM4_HUMAN
Bait Gene NameMDM4
Bait OrganismHomo sapiens (Human)
Sequence Position398-402
Critical ResiduesP4
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Classical fluorescence spectroscopy; Pull down; Mutation analysis; X-ray crystallography
Interaction ID21043
Interacting DomainMATH domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)20713061
CommentsThe N-terminal TRAF-like domain of human Deubiquitinating enzyme USP7 binds to a P/AXXS motif (398-402) in human P53-binding protein MDM4/MDMX

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)