Instance ID11048
Regular ExpressionPxE[^P]xS[^P]
Motif InstancePGEGPST
Bait Uniprot AccessionP03211
Bait Uniprot IdentifierEBNA1_EBVB9
Bait Gene NameEBNA1
Bait OrganismEpstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4)
Sequence Position442-448
Critical ResiduesP3; P6
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Pull down; Mutation analysis; Classical fluorescence spectroscopy; X-ray crystallography
Interaction ID21048
Interacting DomainMATH domain
Disease Association(s)Epstein-Barr Virus (EBV) infection
Inhibitor(s)Unknown
Reference(s)15808506
CommentsThe N-terminal TRAF-like domain of human Deubiquitinating enzyme USP7 (also known as HAUSP) binds to a P/AXXS motif in the Epstein-Barr nuclear antigen 1 (EBNA1) protein of Epstein-Barr virus (EBV) and may contribute to the survival of Epstein-Barr virus-infected cells

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)