Instance ID11050
Regular ExpressionPPxY
Motif InstancePPPY
Bait Uniprot AccessionQ14118
Bait Uniprot IdentifierDAG1_HUMAN
Bait Gene NameDAG1
Bait OrganismHomo sapiens (Human)
Sequence Position889-992
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructurePPII helix
Experimental Method(s)X-ray crystallography
Interaction ID21050
Interacting DomainWW domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10932245
CommentsThe C-terminal region of human Dystrophin (DMD) binds the cytoplasmic tail of human Dystroglycan (DAG1) through the interaction of its WW domain with a proline-rich motif in the tail of DAG1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)