Instance ID11053
Regular ExpressionPPxY
Motif InstancePPPY
Bait Uniprot AccessionP13285
Bait Uniprot IdentifierLMP2_EBVB9
Bait Gene NameLMP2
Bait OrganismEpstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4)
Sequence Position98-101
Critical ResiduesP4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; Co-IP
Interaction ID21053
Interacting DomainWW domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11046148
CommentsThe PY motif of Epstein-Barr virus Latent membrane protein 2 (LMP2) binds to the WW domain of human E3 ubiquitin-protein ligase ITCH/AIP4 and may thereby regulate B-cell receptor (BCR) signaling

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)