Instance ID11064
Regular ExpressionPPxY
Motif InstancePPPY
Bait Uniprot AccessionO15350
Bait Uniprot IdentifierP73_HUMAN
Bait Gene NameTP73
Bait OrganismHomo sapiens (Human)
Sequence Position484-487
Critical ResiduesP4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Co-IP; Pull down(GST tag); Pull down(His tag); Mutation analysis
Interaction ID21064
Interacting DomainWW domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11278685
CommentsThe PPXY motif of human Tumor protein TP73 provides a binding site for human transcription coactivator Yes-associated protein (YAP1/YAP65)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)