Instance ID11065
Regular ExpressionPPxY
Motif InstancePPPY
Bait Uniprot AccessionP03345
Bait Uniprot IdentifierGAG_HTL1A
Bait Gene Namegag
Bait OrganismHuman T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1)
Sequence Position118-121
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Classical fluorescence spectroscopy
Interaction ID21065
Interacting DomainWW domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)14998512
CommentsThe PPXY motif of the Gag polyprotein of human T-cell leukemia virus type 1 (HTLV-1) that binds to the WW domain of Human E3 ubiquitin-protein ligase NEDD4

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)