Instance ID11069
Regular ExpressionPPxY
Motif InstancePPVY
Bait Uniprot AccessionP09450
Bait Uniprot IdentifierJUNB_MOUSE
Bait Gene NameJunb
Bait OrganismMus musculus (Mouse)
Sequence Position176-179
Critical ResiduesP4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Ubiquitinase assay; Co-IP; Pull down; Mutation analysis
Interaction ID21069
Interacting DomainWW domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11828324
CommentsThe PPXY motif of mouse Transcription factor Jun-b that binds to the WW domain of mouse E3 ubiquitin-protein ligase Itch and induces ubiquitination of Jun-b

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)