Instance ID11084
Regular Expressionxxx([ST])Px
Motif InstanceLLPTPP
Bait Uniprot AccessionP01106
Bait Uniprot IdentifierMYC_HUMAN
Bait Gene NameMYC
Bait OrganismHomo sapiens (Human)
Sequence Position55-60
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Thr-P4
Secondary StructureUnknown
Experimental Method(s)Pull down; Western blot; Alanine scanning
Interaction ID21084
Interacting DomainWW domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)15048125
CommentsThe human Peptidyl-prolyl cis-trans isomerase PIN1 binds to the phosphorylated Thr-58-Pro motif of human MYC proto-oncogene protein

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)