Instance ID11096
Regular Expressionxxx([ST])Px
Motif InstanceFAFSPP
Bait Uniprot AccessionQ01860
Bait Uniprot IdentifierPO5F1_HUMAN
Bait Gene NamePOU5F1
Bait OrganismHomo sapiens (Human)
Sequence Position9-14
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4
Secondary StructureUnknown
Experimental Method(s)Western blot; Phosphatase assay; Pull down; Mutation analysis
Interaction ID21096
Interacting DomainWW domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)21296877
CommentsThe human Peptidyl-prolyl cis-trans isomerase PIN1 interacts with the phosphorylated Ser(12)-Pro motif of human Octamer-binding protein 4 (OCT4/POU5F1) and functions as a putative regulator of the induction and maintenance of pluripotency

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)