Instance ID11102
Regular Expressionxxx([ST])Px
Motif InstanceSSPSPS
Bait Uniprot AccessionP69713
Bait Uniprot IdentifierX_HBVA3
Bait Gene NameX
Bait OrganismHepatitis B virus genotype A2 subtype adw2 (strain Rutter 1979) (HBV-A)
Sequence Position38-43
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4
Secondary StructureUnknown
Experimental Method(s)Alanine scanning; Co-IP; Pull down(GST tag)
Interaction ID21102
Interacting DomainWW domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)17383430
CommentsThe human Peptidyl-prolyl cis-trans isomerase PIN1 interacts with the Ser-41-Pro motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)