Instance ID11106
Regular Expressionxxx([ST])Px
Motif InstanceSPKSPS
Bait Uniprot AccessionQ8BT07
Bait Uniprot IdentifierCEP55_MOUSE
Bait Gene NameCep55
Bait OrganismMus musculus (Mouse)
Sequence Position423-428
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4
Secondary StructureUnknown
Experimental Method(s)Phosphatase assay; Alanine scanning; Pull down
Interaction ID21106
Interacting DomainWW domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)19638580
CommentsThe mouse peptidyl-prolyl isomerase Pin1 regulates the final stages of cytokinesis by binding to the Ser-426-Pro motif of mouse Centrosomal protein of 55 kDa (Cep55), an essential component of the midbody ring

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)