Instance ID11109
Regular Expressionxxx([ST])Px
Motif InstanceSPPSPP
Bait Uniprot AccessionP10276
Bait Uniprot IdentifierRARA_HUMAN
Bait Gene NameRARA
Bait OrganismHomo sapiens (Human)
Sequence Position74-79
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4
Secondary StructureUnknown
Experimental Method(s)Western blot; Mutation analysis; Pull down
Interaction ID21109
Interacting DomainWW domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15670742
CommentsThe human Peptidyl-prolyl cis-trans isomerase PIN1 interacts with the phosphorylated Ser-77-Pro motif of human Retinoic acid receptor alpha and induces its degradation

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)