Instance ID11118
Regular Expressionxxx([ST])Px
Motif InstanceTSSSPQ
Bait Uniprot AccessionP04637
Bait Uniprot IdentifierP53_HUMAN
Bait Gene NameTP53
Bait OrganismHomo sapiens (Human)
Sequence Position312-317
Critical ResiduesP4
Motif PTM(s)Phosphorylation at Ser-P4
Secondary StructureUnknown
Experimental Method(s)Pull down; Alanine scanning
Interaction ID21118
Interacting DomainWW domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)12397362
CommentsThe human Peptidyl-prolyl cis-trans isomerase PIN1 interacts with the phosphorylated Ser-315-Pro motif of human Cellular tumor antigen TP53 and is involved in the regulation of its stability and transcriptional activities

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)